代表性论文（#共同第一作者；*通讯作者或共同通讯作者） 1.Wang JJ#, Liu F#, Yang F, Wang YZ, Qi X, Li Y, Hu Q*, Zhu MX*, Xu TL* (2020) Disruption of auto-inhibition underlies conformational signaling of ASIC1a to induce neuronal necroptosis. Nature Communications 11(1): 475. 2.Su X#, Chen M#, Yuan Y, Li Y, Guo SS, Luo HQ, Huang C, Sun W, Li Y, Zhu MX, Liu MG*, Hu J*, Xu TL* (2019) Central Processing of Itch in the Midbrain Reward Center. Neuron, 102, 1-15. 3.Wang Q#, Wang Q#, Song XL, Jiang Q, Wu YJ, Li Y, Yuan TF, Zhang S, Xu NJ, Zhu MX, Li WG*, Xu TL* (2018) Fear extinction requires ASIC1a-dependent regulation of hippocampal-prefrontal correlates. Science Advances, 4(10):eaau3075. 4.Yu Z#, Wu YJ#, Wang YZ, Liu DS, Song XL, Jiang Q, Li Y, Zhang SY, Xu NJ, Zhu MX, Li WG*, Xu TL* (2018) ASIC1a mediates striatal synapse remodeling and procedural motor learning. Science Signaling, 11(542). pii: eaar4481. 5.Li WG#, Liu MG#, Deng S#, Liu YM, Shang L, Ding J, Hsu TT, Jiang Q, Li Y, Li F*, Zhu MX*, Xu TL* (2016) ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion. Nature Communications, 7: 13770. 6.Wang YZ#, Wang JJ#, Huang Y, Liu F, Zeng WZ, Li Y, Xiong ZG, Zhu MX, Xu TL* (2015) Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction. eLife.4: e05682. 7.Peng Z#, Li WG#, Huang C, Jiang YM, Wang X, Zhu MX, Cheng X*, Xu TL* (2015) ASIC3 mediates itch sensation in response to coincident stimulation by acid and nonproton ligand. Cell Reports, 13(2): 387-398. 8.Wang YZ, Zeng WZ, Xiao X, Huang Y, Song XL, Yu Z, Tang D, Dong XP, Zhu MX, Xu TL* (2013) Intracellular ASIC1a regulates mitochondrial permeability transition-dependent neuronal death. Cell Death and Differentiation, 20: 1359-1369. 9.Zeng WZ, Liu DS, Duan B, Song XL, Wang X, Wei D, Jiang W, Zhu MX, Li Y, Xu TL* (2013) Molecular mechanism of constitutive endocytosis of acid-sensing ion channel 1a and its protective function in acidosis-induced neuronal death. Journal of Neuroscience, 33(16): 7066-7078. 10.Wang X, Li WG, Yu Y, Xiao X, Cheng J, Zeng WZ, Peng Z, Zhu MX, Xu TL* (2013) Serotonin facilitates peripheral pain sensitivity in a manner that depends on the nonproton ligand sensing domain of ASIC3 channel. Journal of Neuroscience, 33(10): 4265-4279. 11.Duan B#, Liu DS#, Huang Y, Zeng WZ, Wang X, Yu H, Zhu MX, Chen ZY, Xu TL* (2012) PI3-kinase/Akt pathway-regulated membrane insertion of Acid-sensing ion channel 1a underlies BDNF-induced pain hypersensitivity. Journal of Neuroscience, 32(18): 6351-6363. 12.Duan B#, Wang YZ#, Yang T, Chu XP, Yu Y, Huang Y, Cao H, Hansen J, Simon RP, Zhu MX, Xiong ZG, Xu TL* (2011) Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. Journal of Neuroscience, 31: 2101-2112. 13.Yu Y#, Chen Z#, Li WG#, Cao H, Feng EG, Yu F, Liu H, Jiang H*, Xu TL* (2010) A non-proton ligand sensor in the acid-sensing ion channel. Neuron, 68: 61-72. 14.Pan X#, Gong N#, Zhao J, Yu Z, Gu F, Chen J, Sun X, Zhao L, Yu M, Xu Z, Dong W, Qin Y, Fei G, Zhong C*, Xu TL* (2010) Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice. Brain, 133(5): 1342-1351. 15.Xu TL*, Gong N (2010) Glycine and glycine receptor signaling in hippocampal neurons: diversity, function and regulation. Progress in Neurobiology, 91(4): 349-361. 16.Yang H#, Yu Y#, Li WG, Yu F, Cao H, Xu TL*, Jiang H* (2009) Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism. PLoS Biology, 7(7): e1000151. 17.Xu TL*, Duan B (2009) Calcium-permeable acid-sensing ion channel in nociceptive plasticity: a new target for pain control. Progress in Neurobiology, 87(3): 171-180. 18.Gong N, Li Y, Cai GQ, Niu RF, Fang Q, Wu K, Chen Z, Lin LN, Xu L, Fei J, Xu TL* (2009) GABA transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation. Journal of Neuroscience, 29: 15836-15845. 19.Zhang Z, Gong N, Wang W, Xu L, Xu TL* (2008) Bell-shaped D-serine actions on hippocampal long-term depression and spatial memory retrieval. Cerebral Cortex, 18(10): 2391-2401. 20.Zhang LH#, Gong N#, Fei D, Xu L, Xu TL* (2008) Glycine uptake regulates hippocampal network activity via glycine receptor-mediated tonic inhibition. Neuropsychopharmacology, 33(3):701-711. 21.Duan B, Wu LJ, Yu YQ, Ding Y, Jing L, Xu L, Chen J*, Xu TL* (2007) Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity. Journal of Neuroscience, 27: 11139-11148. 22.Gao J, Duan B, Wang DG, Deng XH, Zhang GY, Xu L, Xu TL* (2005) Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron, 48: 635-646. 专著 《中国大百科全书》第三版（参编） 《生理学名词》第二版（参编） 《神经科学》第三版（参编）；韩济生主编 《神经生物学》第三版（参编）；寿天德主编
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