欧洲杯竞猜平台-百度百科

Name:Huabing Li
Office Location:Room 602, No.5 Bldg., West Area, 280 South Chongqing Rd., Shanghai, China
Telephone:63846590 / 776662
Email:huabing.li@shsmu.edu.cn

Education

2005-2011

Rutgers University / UMDNJ, Piscataway, NJ, USA,

Ph.D.

2002-2005

Nankai University, Tianjin, China,

M.S.

1999-2002

Nankai University, Tianjin, China,

B.S.

Career

2017-present

Shanghai Institute of Immunology Assistant Professor / Principal Investigator

2017-present

Yale University School of Medicine Assistant Professor Adjunct

2012-2017

Yale University Post-Doctoral Fellow

2011-2012

Rutgers University Post-Doctoral Associate

2006-2011

Rutgers University Research Assistant

2002-2005

Nankai University Research & Teaching Assistant

Research Interests

There are more than 100 types of different chemical RNA modification, among which m6A, m1A, m5C, pseudoUridine and APA are the major ones. HBL lab has made a series of pioneering discoveries in the m6A studies, won international reputations in the field, and laid solid experimental foundation. m6A research has been the frontier of the epigenetics field, but it is under explored for other types of RNA modifications, especially the cross-talks among those RNA modifications in response to environmental stimulation are unknown. Immune cells, especially T cells and macrophages in various inflammatory disease and tumor, provide an ideal perspective to explore this frontier. Combine mouse reverse genetics and state-of-art omics techniques, our research focuses on the following areas:

(1) Function of m1A modification in T cells and macrophages;

(2) Function of pseudoUridine modification in T cells and macrophages;

(3) Function of APA modification in T cells and macrophages;

(4) Develop inhibitors to those RNA modification and apply to tumor immunotherapy;

(5) Cross-talks of those RNA modifications.

Lab Website:
https://huabingli.wixsite.com/lilab