Research
  • Name:Xiaoyin Niu

  • Office Location:Room 1111, No.5 Bldg., West Campus, 280 South Chongqing Rd.,Shanghai

  • Telephone:86-021-63846590-776564

  • Email:niuxiaoyin@163.com


Education


2006-2011 Shanghai Jiaotong University Ph.D.
1999-2004 Shanghai Second Medical University Bachelor of Medicine

Career

2014-present Shanghai Insititue of Immunology, Department of Immunology and Microbiology,     Associate Professor
2010-2014 Shanghai Insititue of Immunology, Department of Immunology and Microbiology,     Lecturer
2004-2010 Shanghai Insititue of Immunology,     Assistant

Research Interests

The research in my laboratory focuses on the pathogenesis and immune regulation of autoimmune diseases, such as rheumatoid arthritis and inflammatory bowel disease, especially Th subsets differentiation and their roles in autoimmune diseases.


1.  Zhou L, Cao T, Wang Y, Yao H, Du G, Chen G, Niu X, Tang G.Frequently Increased but Functionally Impaired CD4+CD25+ Regulatory T Cells in Patients with Oral Lichen Planus.Inflammation,2016,39(3):1205-15.   [Link]

2.  Xu Y, Zhu Q, Song J, Liu H, Miao Y, Yang F, Wang F, Cheng W, Xi Y, Niu X, He D, Chen G .Regulatory Effect of Iguratimod on the Balance of Th Subsets and Inhibition of Inflammatory Cytokines in Patients with Rheumatoid Arthritis.Mediators Inflamm,2015,2015:356040 .   [Link]

3.  Li C, Xi Y, Li S, Zhao Q, Cheng W, Wang Z, Zhong J, Niu X, Chen G .Berberine ameliorates TNBS induced colitis by inhibiting inflammatory responses and Th1/Th17 differentiation .Mol Immunol,2015,67(2 Pt B):444-54.   [Link]

4.  Cheng W, Zhao Q, Xi Y, Li C, Xu Y, Wang L, Niu X, Wang Z, Chen G.IFN-β inhibits T cells accumulation in the central nervous system by reducing the expression and activity of chemokines in experimental autoimmune encephalomyelitis .Mol Immunol,2015,64(1):152-62 .   [Link]

5.  Niu X, Chen G.Clinical biomarkers and pathogenic-related cytokines in rheumatoid arthritis.J Immunol Res,2014,2014:698192.   [Link]

6.  Xiaoyin Niu, Guangjie Chen.IL-21 and Related Diseases.J Clin Cell Immunol,2013,2013.   [Link]

7.  Shan Li, Xiaoyin Niu, Yebin Xi, Shaohua Deng, Chengzhen Li, Qing Zhao, Guangjie Chen.T Cell Vaccination Inhibits Th1/Th17/Tfh Frequencies and Production of Autoantibodies in Collagen-Induced Arthritis.Clinical and Developmental Immunology ,2013,2013:967301 .   [Link]

8.  Yang XO, Zhang H, Kim BS, Niu X, Peng J, Chen Y, Kerketta R, Lee YH, Chang SH, Corry DB, Wang D, Watowich SS, Dong C .The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation.Nat Immunol,2013,14(7):732-40 .   [Link]

9.  Tong Z, Yang XO, Yan H, Liu W, Niu X, Shi Y, Fang W, Xiong B, Wan Y, Dong C. A protective role by interleukin-17F in colon tumorigenesis .PLoS One,2012,7(4):e34959 .   [Link]

10.  Niu X, He D, Deng S, Li W, Xi Y, Xie C, Jiang T, Zhang JZ, Dong C, Chen G .Regulatory immune responses induced by IL-1 receptor antagonist in rheumatoid arthritis.Mol Immunol,2011,49(1-2):290-6 .   [Link]

11.  Niu X, He D, Zhang X, Yue T, Li N, Zhang JZ, Dong C, Chen G.IL-21 regulates Th17 cells in rheumatoid arthritis.Hum Immunol,2010,71(4):334-41.   [Link]

12.  Chen G, Zhang X, Li R, Fang L, Niu X, Zheng Y, He D, Xu R, Zhang JZ.Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis.Arthritis Rheum,2010,62(10):2900-8.   [Link]

13.  Deng S, Xi Y, Wang H, Hao J, Niu X, Li W, Tao Y, Chen G .Regulatory effect of vasoactive intestinal peptide on the balance of Treg and Th17 in collagen-induced arthritis.Cell Immunol,2010, 265(2):105-10 .   [Link]

14.  Chen M, Chen G, Nie H, Zhang X, Niu X, Zang YC, Skinner SM, Zhang JZ, Killian JM, Hong J .Regulatory effects of IFN-beta on production of osteopontin and IL-17 by CD4+ T Cells in MS.Eur J Immunol,2009,39(9):2525-36.   [Link]


                 

Copyright 2016. Shanghai Institute of Immunology,Shanghai Jiao Tong University School of Medicine.All Rights Reserved.