Research
  • Name:Hong Nie

  • Office Location:Room 906, 280 South Chongqing Road, Shanghai, China

  • Telephone:86-21-63846590 ext. 776364

  • Email:hnie0823@126.com


Education


1987-1993 Shanghai Second Medical University B.S.



1993-1996 Shanghai Second Medical University M.S.



2001-2004 Shanghai Second Medical University Ph.D.



Career

1996-1997 Shanghai Second Medical University     Teaching Assistant
1997-1998 Konstanz University     Visiting Scholar
1998-1999 Shanghai Second Medical University     Teaching Assistant
1999-2004 Shanghai Second Medical University     Assistant Research Fellow
2005-2005 Baylor College of Medicine     Postdoctoral Fellow
2005-2013 Shanghai Jiao Tong University School of Medicine     Associate Research Fellow
2013-present Shanghai Jiao Tong University School of Medicine     Research Fellow
2016-present Shanghai Jiao Tong University School of Medicine     Principal Investigator

Research Interests


1.Mechanism study of autoimmune diseases

2.Translational research of tumor immunotherapy


1.  Zheng Y, Sun L, Jiang T, Zhang D, He D, Nie H..TNFa promotes Th17 cell differentiation through IL-6 and IL-1b produced by monocytes in rheumatoid arthritis..J Immunol Res.,2014,385352.   [Link]

2.  Nie H, Zheng Y, Li R, Guo TB, He D, Fang L, Liu X, Xiao L, Chen X, Wan B, Chin YE, Zhang JZ..Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-a in rheumatoid arthritis. .Nat Med. ,2013,19(3): 322-8.   [Link]

3.  Sun Q, Zheng Y, Zhang X, Hu X, Wang Y, Zhang S, Zhang D, Nie H. .Novel immunoregulatory properties of EGCG on reducing inflammation in EAE..Front Biosci (Landmark Ed).,2013,18: 332-42.   [Link]

4.  Dang S, Peng Y, Ye L, Wang Y, Qian Z, Chen Y, Wang X, Lin Y, Zhang X, Sun X, Wu Q, Cheng Y, Nie H, Jin M, Xu H. .Stimulation of TLR4 by LMW-HA induces metastasis in human papillary thyroid carcinoma through CXCR7..Clin Dev Immunol. ,2013,712561.   [Link]

5.  Yin Q, Liu C, Wu Y, Wu S, Wang Y, Zhang X, Hu X, Pu J, Lu Y, Zhou H, Wang H, Nie H, Sun H, Chen G..Preventive and therapeutic effects of adenanthin on experimental autoimmune encephalomyelitis by inhibiting NF-kB signaling. .J Immunol.,2013,191(5): 2115-25.   [Link]

6.  Chen M, Chen, Nie H, Zhang X, Niu X, Zhang Y C.Q., Skinner SM, Zhang JW, Killian JM, Hong J.Regulatory effects of IFN-beta on production of osteopontin and IL-17 by CD4+ T Cells in MS..Eur J Immunol ,2009, 39 (9): 2525-36.   [Link]

7.  Nie H, Wu J, Zhang M, Xu J, Zou M..Endothelial nitric oxide synthase-dependent tyrosine nitration of prostacyclin synthase in diabetes in vivo..Diabetes,2006,55 (11): 3133-41.   [Link]

8.  Wan B, Nie H, Liu A, Feng G, He D, Xu R, Zhang Q, Dong C, Zhang JW. .Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis. .J Immunol.,2006,177 (12): 8844-50.   [Link]

9.  Hong J, Zang Y, Nie H, Zhang JW..CD4+ regulatory T cell responses induced by T cell vaccination in patients with multiple sclerosis. .Proc Natl Acad Sci U S A. ,2006,103(13): 5024-29.   [Link]

10.  Xu G, Nie H, Li N, Zheng W, Zhang D, Feng G, Ni L, Xu R, Hong J, Zhang JZ. .Role of osteopontin in amplification and perpetuation of rheumatoid synovitis..J Clin Invest. ,2005,115(4): 1060-7.   [Link]

11.  Sun W, Nie H, Li N, Zang Y C.Q., Zhang D, Feng G, Ni L, Xu R, S Prasad, RR Robinson, W Ho, E Sercarz, Zhang JZ.Skewed T-cell receptor BV14 and BV16 expression and shared CDR3 sequence and common sequence motifs in synovial T cells of rheumatoid arthritis. .Genes Immun.,2005,6(3): 248-61.   [Link]


Yuanyang Yuan,Ph.D.

Assistant Research Fellow

E-mail:sunralmega@126.com


Jun Bai,B.S

Engineer

E-mail:boer_bj@163.com


Yuanteng Zhang,M.S

Assistant Engineer

E-mail:zhangyuanteng@outlook.com


Yongshuai Jiang

Ph.D. Candidate (Class 2016)

E-mail:871781748@qq.com


Haiyan Xu

M.S. Candidate (Class 2014)

E-mail:uhaiyan8@163.com


Guojue Wang

M.S. Candidate (Class 2015)

E-mail:wgj0422@126.com


Yanxin Chen

M.S. Candidate

E-mail:cyx008@126.com




Lab Location:Room 912, 280 South Chongqing Road, Shanghai, China

Tel:86-21-63846590 ext. 776362









                 

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