周炎烽

职称：副研究员/硕士生导师

学位/学历：博士/研究生

电话：021-63846590转776501

电子邮箱：yfzhou@shsmu.edu.cn

个人简介：

周炎烽，欧洲杯竞猜平台-公共卫生学院宋海云课题组副研究员。于2014和2017年在苏州大学分别获得生物化学与分子生物学硕士学位和化学博士学位。2017年至2020年在欧洲杯竞猜平台从事博士后研究。博士后出站留校工作，并于2020年12月破格晋升为副研究员。主持或参与多项国家级和省部级科研项目。主要从事生物材料的设计、生物学效应及其在重大慢病控制中的应用研究。截至目前，已在Adv. Mater., Nano Today, Angew. Chem. Int. Ed, Biomaterials, Small等国际权威期刊上发表第一作者（含共同）论文15篇，其中有7篇发表于影响因子大于10.0的期刊。

主要研究方向：

① 生物材料在重大慢病控制中的应用及机制研究

聚焦生物医学与材料化学交叉领域，设计开发了多种新型智能药物递送平台，提出了糖尿病及肿瘤等重大慢病控制新策略，为解决重大慢病控制面临的共性问题和挑战提供了新的思路。

② 食品添加用及医用材料的生物效应研究及潜在应用开发

系统考察食品添加用及医用材料的结构、理化性质与其细胞行为学、活体代谢免疫学及毒理学之间的关系，并深入探讨该类材料对细胞信号转导通路的调控机制，探寻其潜在临床应用价值。

代表性研究成果：（IF：影响因子）

【1】Chang Liu, Yanfeng Zhou†*, Daoxia Guo, Yan Huang, Xiaoyuan Ji, Qian Li, Nan Chen*, Chunhai Fan*, Haiyun Song*. Reshaping Intratumoral Mononuclear Phagocytes with Antibody-Opsonized Immunometabolic Virusomes. Adv. Mater., 2023, under review. (共同第一作者；共同通讯作者，IF= 32.086)

【2】Yanfeng Zhou†, Chang Liu†, Yun Yu†, Min Yin, Jinli Sun, Jing Huang, Nan Chen, Hui Wang*, Chunhai Fan*, Haiyun Song*. Organelle-Specific Nanozyme for Diabetes Care in Genetically- or Diet-Induced Models. Adv. Mater., 2020, 32, 2003708. (第一作者，IF= 32.086)

【3】Yanfeng Zhou, Yun Zhang, Yiling Zhong, Rong Fu, Sicong Wu, Qin Wang, Houyu Wang, Yuanyuan Su, Huimin Zhang*, Yao He*. The In Vivo Targeted Molecular Imaging of Fluorescent Silicon Nanoparticles in Caenorhabditis Elegans. Nano Res., 2018, 11, 2336–2346. (第一作者，IF= 10.269)

【4】Yanfeng Zhou†, Qin Wang†, Bin Song, Sicong Wu, Yuanyuan Su, Huimin Zhang*, Yao He*. A Real-Time Documentation and Mechanistic Investigation of Quantum Dots-Induced Autophagy in Live Caenorhabditis Elegans. Biomaterials, 2015, 72, 38-48. (第一作者，IF= 15.304)

【5】Yanfeng Zhou, Xiangxu Jiang, Jia Tang, Yuanyuan Su, Fei Peng, Yimei Lu, Rui Peng*, and Yao He*. A Silicon-Based Antibacterial Material Featuring Robust and High Antibacterial Activity. J. Mater. Chem. B, 2014, 2, 691-697. (第一作者，IF= 7.571)

【6】Yanfeng Zhou†, Chang Liu†, Haiyun Song*. Innate Immunomodulatory Nanodevices for Cancer Therapy: A Review. J. Biomed. Nanotechnol., 2022, 18, 293-318. (第一作者，IF= 3.641)

【7】Qin Wang†, Yi Zhu†, Bin Song, Rong Fu, Yanfeng Zhou*. The In Vivo Toxicity Assessments of Water-Dispersed Fluorescent Silicon Nanoparticles in Caenorhabditis Elegans. Int. J. Environ. Res. Public Health, 2022, 19, 4101. (唯一通讯作者，IF= 4.614)

【8】Chang Liu†, Yanfeng Zhou†, Xiaoyuan Ji, Hui Xie, Xingjie Hu, Min Yin, Nan Chen*, Chunhai Fan*, Haiyun Song*. Nanobooster-encapsulated hybrid RNA as anti-tumor viral mimicry. Nano Today, 2021, 38, 101211. (共同第一作者，IF= 18.962)

【9】Houyu Wang†, Yanfeng Zhou†, Xiangxu Jiang, Bin Sun, Ying Zhu, Hui Wang, Yuanyuan Su, and Yao He*. Simultaneous Capture, Detection, and Inactivation of Bacteria as Enabled by a Surface-Enhanced Raman Scattering Multifunctional Chip. Angew. Chem. Int. Ed., 2015, 54, 5132-5136. (共同第一作者，IF= 16.823)

【10】Qin Wang†, Yanfeng Zhou†, Bin Song, Yiling Zhong, Sicong Wu, Rongrong Cui, Haixia Cong, Yuanyuan Su, Huimin Zhang*, and Yao He*. Linking Subcellular Disturbance to Physiological Behavior and Toxicity Induced by Quantum Dots in Caenorhabditis Elegans. Small, 2016, 12, 23, 3143-3154. (共同第一作者，IF= 15.153)

【11】Teng Liu†, Rui Xing†, Yanfeng Zhou†, Jue Zhang, Yuanyuan Su, Keqin Zhang, Yao He*, Yanghu SiMa*, Shiqing Xu*. Hematopoiesis Toxicity Induced by CdTe Quantum Dots Determined in an Invertebrate Model Organism. Biomaterials, 2014, 35, 2942-2951. (共同第一作者，IF= 15.304)

【12】Rui Xing†, Kaile Li†, Yanfeng Zhou†, Yuanyuan Su, Siqi Yan, Kailong Zhang, Sicong Wu, Yanghu SiMa, Keqin Zhang*, Yao He *, Shiqing Xu*. Impact of Fluorescent Silicon Nanoparticles on Circulating Hemolymph and Hematopoiesis in an Invertebrate Model Organism. Chemosphere, 2016, 159, 628-637. (共同第一作者，IF= 8.943)