Lab Leader: Mingliang Zhang

Lab Name: Laboratory of Stem Cells & Neuroregeneration

Lab Info：Diseases that affect the brain or other parts of the central nervous system raise fascinating questions in neuroscience. Among the most disabling and complex conditions is the interaction of neurons with glial cells, particularly oligodendrocytes, the myelin-producing cells, as well as their functions on the brain. Our group maintains a strong focus on myelin development and dedicates to developing the chemical/genetic tools for remyelination. By combining the cutting-edge technologies of stem cells and chemical biology, we are developing the small-molecule chemicals promoting myelination, deciphering the codes for remyelination, exploring the contribution of myelin-neuron interaction to the neurodevelopment and regeneration, and clarifying the potential roles of myelin formation on improving the dysfunction of cognition and brain aging. We devote ourselves to providing reparative strategies for stimulating endogenous regeneration and ultimately reconstructing brain functions. Supported by the National Key R & D Program of China, the National Natural Science Foundation of China, the Basic Research Program of Shanghai Science and Technology Committee, and the Project of the Shanghai Municipal Education Commission currently, our representative works have been published in journals, including Cell Stem Cell, Cell Rep., and J. Mol. Cell Biol. We are now seeking highly motivated research associates and postdoc fellows with backgrounds in stem cells, neuron biology, and chemical biology, and to work on the projects of myelination biology. Applicants could send a single PDF file with the updated CV and publications to mingliang.zhang@shsmu.edu.cn. Your participation is highly desired.

Lab Members: