Lab Leader: Zeyu Xiao

Lab Name: Laboratory of Visualized Drug Delivery

Lab Info：Our group has been dedicated to develop visualized drug delivery systems with high sensitivity and high selectivity for disease diagnosis and therapy, by using interdisciplinary technologies and methods (e.g. chemistry, biology, pharmacology and molecular imaging). The specific research contents are as follows: (1) Developing visualized drug delivery systems based on in-vivo optical imaging (such as Raman imaging) or nuclear medical imaging technologies, for intra-operative diagnosis and removal of residual micro-tumors, reversing targeted-drug resistance, medication guidance and treatment evaluation; (2) Investigating oral drug delivery system for naked-eye visualization and treatment of colon diseases at the early stage; (3) Designing DNA-modularied programmable bivalent drugs for precise receptor regulation. Recently, we have published more than 40 research articles in the international academic journals (e.g. Chem Soc. Rev., Nature Comm. Angew. Chem., Nano Lett, ACS Nano, Adv Funct Mater., etc), and three Book Chapters. Among them, there has been 1 article cited more than 1000 times, 5 articles cited more than 200 times, 7 articles cited more than 100 times, and 3 articles selected as the highly cited papers by ESI. One visualized drug delivery system has begun clinical trial stage. In addition, we also have applied/authorized two international patents and one domestic patent.

Lab Members: