Lab Leader: Zhou, B.-B.

Lab Name: Laboratory of Cancer Drug Resistance and Genetic Instability

Lab Info：Drug resistance and tumor relapse team mainly uses systems biology approaches (integrated genomics, cellular and molecular biology, biochemistry and animal models) to study the molecular mechanism of pediatric leukemia drug resistance and tumor relapse for both basic and translational intents. The team currently consists of 1 CO-PI, 5 research technicians, 2 postdoctoral fellows and 5 PhD candidates. Three previous postdoctoral fellows had been appointed as associate and assistant professor respectively. Three PhD graduates are engaged in post-doctoral trainings in the United States and China respectively.

Main research areas:

1. Basic mechanism and translational application of drug-resistant and tumor relapse in childhood leukemia.

2. Role of DNA damage response (DDR) in drug-resistant and tumor relapse of childhood leukemia.

3. Drug and tumor metabolism in drug-resistant and tumor relapse of childhood leukemia

Lab Members: