Lab Leader: Jian Zhang

Lab Name: Laboratory of Molecular Design

Lab Info：The Molecular Design Lab was built in September 2009 at the Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, . Our research interests focus on drug discovery using the combination of drug design, bioinformatics, medicinal chemistry and chemical biology methods. Specially, we developed a series of allosteric methods including recognition of allosteric target, identification of allosteric site and allosteric drug screening to overcome potential selectivity and toxicity in the drug discovery. Inspired by the advantage of the methods, novel allosteric activators/inhibitors were discovered in several drug targets and used to address the challenges of finely-tuned biological regulation and human disorder treatment and medicine.

Lab Members: