Lab Leader: Shao-Ming Shen

Lab Name: Laboratory of Aberrant Protein Modification and Cancer

Lab Info：Our laboratory mainly focuses on deciphering the role of aberrant protein post-translational modifications (PTMs) in the development and progress of cancer. Especially, we have made a series of findings to reveal that differentially localized PTEN and different PTEN translational variants are subjected to specific PTMs to play distinct and even opposite roles in the development and progress of cancer (EMBO Rep, 2015; Nature Commun, 2018; Nature Cell Biol, 2019; Nature Commun, 2020).

Lab Members: