Biography

My major research interests are on the mechanism of haemostasis and coagulation and our research team have been primarily working on the structure and function of coagulation and anticoagulation factors. We have disclosed the molecular pathogenesis of thrombophilia and hemophilia by deciphering the function and structural implication of mutations of encoding genes. Our research findings revealed how the balance of the pro- and anti- coagulation was maintained and pathological outcome when the balance was interrupted. By incorporation of laboratory research in the management of patients with bleeding and thrombotic disorders, we are able to make precision diagnosis and establish individualized treatment accordingly. Furthermore, with the identification of the rare gain of function mutation, we have developed novel gene therapy strategy, which provides hope the cure of the hemophilia.

Education / Training

• 1992-1999  Xi’an Medical University, China, Master of Medicine (equivalent to M.D. in U.S), Medicine

• 2001-2004  Shanghai Institute of Hematology Ruijin Hospital affiliated to Shanghai Second Medical University, China, Ph.D. Hematology, Internal Medicine

• 2004-2009  Temple University School of Medicine, Sol Sherry Thrombosis Research Center. Philadelphia, PA. Postdoctoral Fellow, Thrombosis & Biochemistry

Positions and Honors

• 2015.12 ~ present  Shanghai Jiaotong University Associate Scientist School of Medicine, Department of Laboratory Medicine       

• 2009.09 ~ 2015.12  Temple University, Assistant Scientist, School of Medicine, Sol Sherry Thrombosis Research Center

• 2004.10 ~ 2009.09  Temple University, Postdoctoral Fellow, School of Medicine, Sol Sherry Thrombosis Research Center

• 1999.07 ~ 2001.09  Shaanxi Provincial People’s Hospital, Resident, Specialized in Medicine