姓名：胡沁沁

性别：女

出生年月：1989年2月

学位/学历：博士

职称：讲师/助理研究员

电子邮件：qinqinhu@sjtu.edu.cn

办公地址：上海市黄浦区重庆南路280号1号楼412室 

办公电话：021-63846590转776974

教育经历

2007年09月至2011年06月 陕西师范大学，本科

2011年09月至2016年06月 浙江大学，博士

2014年11月至2016年05月 美国阿肯色大学，博士生联合培养

工作经历

2016年06月至2019年06月 复旦大学生物医学研究院，基础医学流动站，博士后

2019年06月至2021年06月 复旦大学生物医学研究院，助理研究员

2021年06月至今           欧洲杯竞猜平台，教师

研究方向/主要研究内容

光学生物/化学传感器；食品安全与环境监测；

功能核酸筛选及其在疾病、化学生物危害识别中的应用

科研/教学研究项目

1.     2021.01-2023.12，适配体-DNA纳米自组装靶向调控GTF2H4在心脏微血管内皮细胞缺血再灌注损伤中的作用及分子机制，82000270，国家自然科学基金青年科学基金项目 （主持）

2.     2021.07-2023.07，级联放大-适配体传感器用于诊断耐药型TNBC外泌体，TMSK-2021-114，转化医学国家重大科技基础设施（上海）开放课题项目 （主持）

主要学术成果

期刊论文

1.        Qinqin Hu^#; Hua   Li^#; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanotechnology   Enabled Drug Delivery systems.” Chemical Reviews 2019, 119(10):   6459-6506. (IF=52.76)

2.        Qinqin Hu^#;   Sheng Wang; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanostructure-Based   Systems for Intelligent Delivery of Therapeutic Oligonucleotides.” Advanced   Healthcare Materials 2018, 7, 1-19. (IF=7.367)

3.        Qinqin   Hu^#; Ronghui   Wang; Hong Wang; Michael F. Slavik; Yanbin Li*. “Selection of   Acrylamide-Specific Aptamers by a Quartz Crystal Microbalance Combined SELEX   Method and Their Application in Rapid and Specific Detection of Acrylamide.” Sensors   and Actuators B: Chemical 2018, 273, 220-227. (IF=7.1)

4.        Qinqin   Hu^#; Yingchun   Fu; Xiahong Xu; Zhaohui Qiao; Ronghui Wang;Ying Zhang; Yanbin Li*. “A   Colorimetric Detection of Acrylamide in Potato Chips Based on   Nucleohile-Initiated Thiol-Ene Michael Addition.” Analyst 2016,   141, 1136-1143. (IF=3.978)

5.        Qinqin   Hu^#;   Xiahong Xu; Yingchun Fu; Yanbin Li*. “Rapid methods for Detecting Acrylamide   in Thermally Processed Foods: A Review.” Food Control 2015, 56,   135-146. (IF=4.258)

6.        Qinqin   Hu^#;   Xiahong Xu; Zhanming Li; Ying Zhang; Jianping Wang; Yingchun Fu; Yanbin Li*.   “Detection of Acrylamide in Potato Chips Using a Fluorescent Sensing Method   Based on Acrylamide Polymerization-Induced Distance Increase Between Quantum   Dots.” Biosensors and Bioelectronics 2014, 54, 64-71. (IF=10.257)

7.        Qinqin   Hu^#; Xiahong   Xu; Zhanming Li; Ying Zhang; Yanbin Li*. “Rapid Detection of Acrylamide in   Food Using a Fluorescent Sensing Method Based on Functional CdSe/ZnS Quantum   Dots.” IEEE Sensors 2013, 414-417. (IF=3.073)

8.        Zongxuan^#,   Tong; Qinqin Hu; Hongzhou Gu*. “Deoxyribozymes: Selection, Biosensing   and Outlook.” Chemical Journal of Chinese Universities-Chinese 2020,   41 (11), 2345-2355. (IF=0.576)

9.        Hong   Wang#*; Lijun Wang; Qinqin Hu; Ronghui Wang; Yanbin Li; Michael Kidd.   “Rapid and Sensitive Detection of Campylobacter jejuni in Poultry Products   Using a Nanoparticle-Based Piezoelectric Immunosensor Integrated with   Magnetic Immunoseparation.” Journal of Food Protection 2018, 81   (8), 1321–1330. (IF= 1.581)

10.      Zhuo   Zhao^#; Lizhou Xu; Qinqin Hu; Ronghui Wang; Hong Wang;   Yanbin Li*. “A portable and automatic biosensing instrument for simultaneous   detection of foodborne pathogens using nanobead-based magnetic separation and   quantum dot-labeled fluorescent measurement.” 2016 ASABE Annual   International Meeting 162461406. (doi:10.13031/aim.20162461406)

11.      Huiyan   Li^#; Fangfei Yin; Xinyi Li; Wannan Jia; Jia Ding; Li Zhang;   Zhonghua Wang; Qinqin Hu; Jieliang Zuo; Huliang Jia; Li hua Wang;   Chunhai Fan*; Hongzhou Gu*; Jian Wu.* “Novel aptasensor-based assay of sonic   hedgehog ligand for detection of portal vein invasion of hepatocellular   carcinoma” Biosensors and Bioelectronics 2021, 174, 112738.   (IF=10.257)

注明：# 第一作者；*   通讯作者

学术会议

1.     Qinqin Hu; A   colorimetric aptasensor for rapid and specific detection of acrylamide based   on selected aptamers by QCM-SELEX method, 2016美国农业工程学会, 奥兰多,   2016.07.26-07.29.

2.     Qinqin Hu; Ronghui Wang;   Yingchun Fu; Xiahong Xu; Yanbin Li; A Portable “Off-On-Off” Fluorescent   Biosensor for Rapid Detection of Acrylamide Based on a Quantum Dot-Hg (II) -   Biothiol System, 2015国际食品工程年会，芝加哥，2015.07.11-07.15

3.     Qinqin Hu; Colorimetric   detection of acrylamide using gold nanoparticles based on the thiol-ene   Michael addition between acrylamide and glutathione, 第26届世界传感器大会, 墨尔本, 2014.05.27-05.30.

专利

1.     徐霞红，胡沁沁，张英，李延斌．基于量子点的荧光法检测热加工食品中丙烯酰胺的方法．ZL201310383303.1

2.     李延斌，胡沁沁，傅迎春，徐霞红，张英．纳米金比色生物传感器快速检测热加工食品中丙烯酰胺的方法．

ZL201510528800.5

3.     顾宏周，胡沁沁，佟宗轩，江一舟，邵志敏，刘西禹，葛丽萍，傅彤．一种富集、鉴定待测病样中分子标志物的方法．（申请号202110361337.5）

4.     顾宏周，胡沁沁，佟宗轩，江一舟，邵志敏，刘西禹，葛丽萍，傅彤．差异筛选特异感应三阴性乳腺癌的脱氧核酶探针．（申请号2021 10364792.0）

开设课程

Ecosystem   Health, Food Systems and Sustainability

Profile

Name:   Qinqin Hu

Gender:   Female

Date   of birth: 1989.02

Degree:   Ph.D.

Academic   Title: Lecturer/Assistant Researcher

Email:   qinqinhu@sjtu.edu.cn                    

Address:   Rm   412, Building 1, 280 South Chongqing Road, Shanghai

Office   Tel: 021-63846590   * 776974

Education

2007.09   to 2011.06, Shaanxi Normal University, Bachelor’s Degree

2011.09   to 2016.06, Zhejiang University, PhD

2014.11   to 2016.05, University of Arkansas, Joint PhD student (CSC funding)

Appointments

2016.06   to 2019.06, Institutes of Biomedicine, Fudan University, Postdoc Training

2019.06   to 2021.06, Institutes of Biomedicine, Fudan University, Assistant Researcher

2021.06 to current, Shanghai Jiao Tong   University School of Medicine, Lecturer/Assistant Researcher

Research   interest

Optical   bio/chem-sensors for food safety and environmental surveillance;

Functional   nucleic acid probes for specifically sensing diseases, chemical or biological   hazards

Projects

1.      2021.01-2023.12,   Targeting regulation of GTF2H4 by Aptamer-DNA nanoassembly in   ischemia-reperfusion injury and its mechanisms, 82000270, Youth Foundation of   National Natural Science Foundation of China

2.      2021.07-2023.07,   Aptasensors with cascades amplification for diagnosis of TNBC exosomes,   TMSK-2021-114, National Facility of Translational Medicine (Shanghai)

Publications

1.        Qinqin Hu^#; Hua   Li^#; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanotechnology   Enabled Drug Delivery systems.” Chemical Reviews 2019, 119(10):   6459-6506. (IF=52.76)

2.        Qinqin Hu^#;   Sheng Wang; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanostructure-Based   Systems for Intelligent Delivery of Therapeutic Oligonucleotides.” Advanced   Healthcare Materials 2018, 7, 1-19. (IF=7.367)

3.        Qinqin   Hu^#; Ronghui   Wang; Hong Wang; Michael F. Slavik; Yanbin Li*. “Selection of   Acrylamide-Specific Aptamers by a Quartz Crystal Microbalance Combined SELEX   Method and Their Application in Rapid and Specific Detection of Acrylamide.” Sensors   and Actuators B: Chemical 2018, 273, 220-227. (IF=7.1)

4.        Qinqin   Hu^#; Yingchun   Fu; Xiahong Xu; Zhaohui Qiao; Ronghui Wang;Ying Zhang; Yanbin Li*. “A   Colorimetric Detection of Acrylamide in Potato Chips Based on   Nucleohile-Initiated Thiol-Ene Michael Addition.” Analyst 2016,   141, 1136-1143. (IF=3.978)

5.        Qinqin   Hu^#;   Xiahong Xu; Yingchun Fu; Yanbin Li*. “Rapid methods for Detecting Acrylamide   in Thermally Processed Foods: A Review.” Food Control 2015, 56,   135-146. (IF=4.258)

6.        Qinqin   Hu^#;   Xiahong Xu; Zhanming Li; Ying Zhang; Jianping Wang; Yingchun Fu; Yanbin Li*.   “Detection of Acrylamide in Potato Chips Using a Fluorescent Sensing Method   Based on Acrylamide Polymerization-Induced Distance Increase Between Quantum   Dots.” Biosensors and Bioelectronics 2014, 54, 64-71. (IF=10.257)

7.        Qinqin   Hu^#; Xiahong   Xu; Zhanming Li; Ying Zhang; Yanbin Li*. “Rapid Detection of Acrylamide in   Food Using a Fluorescent Sensing Method Based on Functional CdSe/ZnS Quantum   Dots.” IEEE Sensors 2013, 414-417. (IF=3.073)

8.        Zongxuan^#,   Tong; Qinqin Hu; Hongzhou Gu*. “Deoxyribozymes: Selection, Biosensing   and Outlook.” Chemical Journal of Chinese Universities-Chinese 2020,   41 (11), 2345-2355. (IF=0.576)

9.        Hong   Wang#*; Lijun Wang; Qinqin Hu; Ronghui Wang; Yanbin Li; Michael Kidd.   “Rapid and Sensitive Detection of Campylobacter jejuni in Poultry Products   Using a Nanoparticle-Based Piezoelectric Immunosensor Integrated with   Magnetic Immunoseparation.” Journal of Food Protection 2018, 81   (8), 1321–1330. (IF= 1.581)

10.      Zhuo   Zhao^#; Lizhou Xu; Qinqin Hu; Ronghui Wang; Hong Wang;   Yanbin Li*. “A portable and automatic biosensing instrument for simultaneous   detection of foodborne pathogens using nanobead-based magnetic separation and   quantum dot-labeled fluorescent measurement.” 2016 ASABE Annual   International Meeting 162461406. (doi:10.13031/aim.20162461406)

11.      Huiyan   Li^#; Fangfei Yin; Xinyi Li; Wannan Jia; Jia Ding; Li Zhang;   Zhonghua Wang; Qinqin Hu; Jieliang Zuo; Huliang Jia; Li hua Wang;   Chunhai Fan*; Hongzhou Gu*; Jian Wu.* “Novel aptasensor-based assay of sonic   hedgehog ligand for detection of portal vein invasion of hepatocellular   carcinoma” Biosensors and Bioelectronics 2021, 174, 112738.   (IF=10.257)

notes：#   first author；* corresponding author

Conferences

1.     Qinqin Hu; A colorimetric   aptasensor for rapid and specific detection of acrylamide based on selected   aptamers by QCM-SELEX method, 2016ASABE, Orlando,   2016.07.26-07.29.

2.     Qinqin Hu; Ronghui Wang;   Yingchun Fu; Xiahong Xu; Yanbin Li; A Portable “Off-On-Off” Fluorescent   Biosensor for Rapid Detection of Acrylamide Based on a Quantum Dot-Hg (II) -   Biothiol System, 2015IFT,   Chicago, 2015.07.11-07.15

3.     Qinqin Hu; Colorimetric   detection of acrylamide using gold nanoparticles based on the thiol-ene   Michael addition between acrylamide and glutathione, Word Congress of Biosensors, Melbourne, 2014.05.27-05.30.

Patents

1.     Xiahong Xu, Qinqin Hu,   Ying Zhang, Yanbin Li. A fluorescent method for the detection of acrylamide   in thermally processed foods. ZL201310383303.1

2.     Yanbin Li, Qinqin   Hu, Yingchun Fu, Xiahong Xu, Ying Zhang. A colorimetric approach for   rapid detection of acrylamide in thermally   processed foods. ZL201510528800.5

3.     Hongzhou Gu, Qinqin   Hu, Zongxuan Tong, Yizhou Jiang, Zhimin Shao, Xiyu Liu, Liping Ge, Tong   Fu. A method to concentrate and identify the molecular markers of disease.   (No. 202110361337.5)

4.     Hongzhou Gu, Qinqin   Hu, Zongxuan Tong, Yizhou Jiang, Zhimin Shao, Xiyu Liu, Liping Ge, Tong   Fu. Selection of DNAzymes that specifically sense triple negative breast   cancers. (No. 202110364792.0)

Lectures

Ecosystem Health, Food Systems and   Sustainability