课题组长简介

Florent Ginhoux，欧洲杯竞猜平台上海市免疫学研究所客座教授，新加坡免疫学联网（Singapore Immunology Network）高级研究员，新加坡免疫学会副主席。主要从事树突状细胞、单核细胞和巨噬细胞发育研究，是该领域顶尖的科学家之一。近三年内在Nature、Science、Cell、Nature Immunology、Immunity等杂志发表大量研究论文。

Florent Ginhoux在上海市免疫学研究所的实验室主要从事单核-巨噬细胞的发育和功能研究，研究工作发表于2019年Cell杂志。单核-巨噬细胞是肿瘤微环境中数量多的免疫细胞群体，和微环境中其他细胞类群具有广泛的交流，在调控肿瘤免疫微环境中起到核心作用，是有价值的肿瘤免疫治疗靶标。靶向这些细胞需要对其发育过程和控制其稳态的机制有深入的了解，我们将从发育学角度出发，使用能够对单核细胞进行示踪的动物模型来深入研究这些科学问题，以期开发靶向这些细胞的肿瘤治疗方案。我们希望有志于此的青年博士加入我们，共同努力！

相关连接

Florent Ginhoux课题组 ：DetailMemberInfo.php?pid=6&cid=114&num=114&id=19

https://www.a-star.edu.sg/docs/librariesprovider26/publication/publications_florent-ginhoux-(updated-19nov2020).pdf

岗位要求：

1. 获得（或即将获得）免疫学、分子生物学、细胞生物学、生物化学或医学相关专业博士学位；入站时获得博士学位的时间不超过三年，年龄35周岁以下。

2. 具有良好的英语交流和写作能力；

3. 科学态度严谨，思维活跃，有好奇心，具有较强的工作责任心和团队协作精神；

岗位待遇：

1. 课题组将为博后提供大量接触该领域顶尖科学家的机会；提供良好的个人发展平台，提供出国学习和参加国际会议等访问交流机会

2. 提供具有竞争性的待遇和相关福利。具体按照欧洲杯竞猜平台和上海市免疫学研究所相关标准执行。

申请方式：请将个人简历（英文）发至Florent_Ginhoux@immunol.a-star.edu.sg。邮件标题请注明应聘博士后。应聘材料将予以保密。

Postdoc advertisement

Florent Ginhoux's lab at the Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine is recruiting 2 postdocs (PhD or MD/PhD) with an immunology background and expertise in the field of myeloid cells and tumor immunology.

Please visit our lab website for details: (DetailMemberInfo.php?pid=6&cid=114&num=114&id=19)

About the PI

Florent Ginhoux is a Senior Principal Investigator at the Singapore Immunology Network (SIgN), A*STAR and an Adjunct Professor at the Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine. He is one of the top scientists in the field of myeloid cells, and has published works in Nature, Science, Cell, Immunity and Nature Immunology as a corresponding author (full list of publications: https://www.a-star.edu.sg/docs/librariesprovider26/publication/publications_florent-ginhoux-(updated-19nov2020).pdf). Research in the lab focuses on understanding the ontogeny and function of myeloid cells in both humans and mice, as well as the function of these cells in tumor immunology. In 2019, we generated a monocyte fate mapping model that could distinguish macrophages with different developmental origins (embryonic or monocyte-derived) and published our findings in Cell, paving the way to investigating the function of macrophages with different origins in tumors. Myeloid cells are the most abundant populations in the tumor microenvironment and are key mediators of cellular cross-talk, and are thereby valuable therapeutic targets. Potential intervention strategies aiming at manipulation of these cells will require in-depth insights of their origins and the mechanisms that govern their homeostasis. Through the use of Ms4a3 monocyte fate mapping models, we can begin to have a clearer understanding of these questions.

Postdoc positions

The Ginhoux lab is looking for highly motivated and talented scientists to address the fundamental questions in the field of myeloid cells. Candidates with Ph.D., M.D., degrees that interested in understanding the ontogeny and function of myeloid cells in tumor biology are welcome to apply. Please email your CV, a brief description of your previous work and your future research interests to Florent_Ginhoux@immunol.a-star.edu.sg, if interested.

Contact Information:

Tel: 021-63846590-776733

email: Florent_Ginhoux@immunol.a-star.edu.sg