1.Yang XD, Li W, Zhang S, Wu D, Jiang X, Tan R, Niu X, Wang Q, Wu X, Liu Z, Chen LF, Qin J, Su B. ,PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.,EMBO J,2020,39(2):e102201.[Link]

2.Zhang YS, Xin DE, Wang Z, Song X, Sun Y, Zou QC, Yue J, Zhang C, Zhang JM, Liu Z, Zhang X, Zhao TC, Su B, Chin YE.,STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation.,EMBO J,2019,38(6).[Link]

3.Liu Z, Gu Y, Chakarov S, Bleriot C, Kwok I, Chen X, Shin A, Huang W, Dress RJ, Dutertre CA, Schlitzer A, Chen J, Ng LG, Wang H, Liu Z, Su B, Ginhoux F.,Fate mapping via Ms4a3 expression history traces monocyte-derived cells.,Cell ,2019,178(6):1509-1525.[Link]

4.Hu ZL, Qu GJ, Yu XY, Jiang HJ, Teng XL, Ding L, Hu QW, Guo WX, Zhou Y,Wang F, Li HB, Chen L, Jiang J, Su B, Liu JL, Zou Q.,Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+T Cells.,Cell Metabolism ,2019,30(2):290-302.[Link]

5.M Li, AS Lazorchak, X Ouyang, H Zhang, H Liu, O.A Arojo, G Qu, X Xu, X Liu, W Zhang, Q Wang, D Liu, F Li,B Su.,Sin1/mTORC2 regulates B cell growth and metabolism via mTORC1 and Myc activation.,Cell Mol Immunol,2019,16(9):757-769.[Link]

6.X Ouyang, Y Han, G Qu, M Li, O Arojo, H Sun, X Liu, D Liu, LChen, Q Zou, Bing Su.,Metabolic regulation of T cell development by Sin1-mTORC2 is mediated by pyruvate kinase M2.,J Mol Cell Biol,2019,11(2):93-106.[Link]

7.OA. Arojo, X Ouyang, D Liu, T Meng, SM. Kaech, JP. Pereira and B Su.,Active mTORC2 Signaling in Naive T Cells Suppresses Bone Marrow Homing by Inhibiting CXCR4 Expression.,J Immunol,2018,201(3):908-915.[Link]

8.Xuemei Fan, Conghui Wang, Panlai Shi, Wen Gao, Jianmin Gu, Yan Geng, Wenlong Yang, Ningbo Wu, Yang Wang, Yanyan Xu, Xue Chen, Lin Zhang, Kemin Wang,Bing Su and Junling Liu.,Platelet MEKK3 regulates arterial thrombosis and myocardial infarct expansion in mice.,Blood Adv,2018,2(12):1439-1448.[Link]

9.Wu ZR, Yan LC, Liu YT, Cao L, Guo YH, Zhang Y, Yao H, Cai L, Shang HB, Rui WW, Yang G, Zhang XB, Tang H, Wang Y, Huang JY, Wei YX, Zhao WG, Su B and Wu ZB.,Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours,Nature Communications,2018,9(1):4624.[Link]

10.Xu YY, Ouyang XX, Yan LC, Zhang ML, Hu ZL, Gu JM, Fan XM, Zhang L, Zhang JF, Xue S, Chen GQ, Su B, and Liu JL.,Sin1 regulates ischaemia-induced microthrombosis through integrin αIIbβ3-mediated outside-in signaling and hypoxia responses in platelets, Arteriosclerosis, Thrombosis, and Vascular Biology,2018,38(12): 2793-2805.[Link]

11.Zepp JA, Zhao J, Liu C, Bulek K, Wu L, Chen X, Hao Y, Wang Z, Wang X, Ouyang W, Kalady MF, Carman J, Yang WP, Zhu J, Blackburn C Huang YH, Hamilton TA1,2, Su B and LiX.,IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis.,J Immunol,2017,199(11):3849-3857.[Link]

12.Tan R, Nakajima S, Wang Q, Sun H,Xue J, Wu J, Hellwig S, Zeng X, Yates NA7, Smithgall TE, Lei M, Jiang Y, Levine AS, Su B, Lan L.,Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1.,Mol Cell,2017,65(5):818-831.[Link]

13.Wang Q, Tan R, Zhu X, Zhang Y, Tan Z, Su B，Li Y.,Oncogenic K-ras confers SAHA resistance by up-regulating HDAC6 and c-myc expression.,Oncotarget,2016,7(9):10064-72.[Link]

14.Pengda Liu, Wenjian Gan, Y. Rebecca Chin, Kohei Ogura, Jianping Guo, Jinfang Zhang, Bin Wang, Blenis J, Cantley LC, Toker A, Su B，Wei W.,PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.,Cancer Discov,2015,5(11):1194-209.[Link]

15.Fisher OS, Deng H, Liu D, Zhang Y, Wei R, Deng Y, Zhang F, Louvi A, Turk BE, Boggon TJ, Su B.,Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex.,Nat Commun,2015,6:7937.[Link]

16.Xing Chang, Fang Liu, Xiaofang Wang, and Su B.,MEKK2 and MEKK3 regulate TGF-b-mediated helper T cell differentiation.,Immunity,2011,34: 201-212.[Link]

17.Valeria Facchinetti, Weiming Ouyang, Hua Wei, Nelyn Soto, Adam Lazorchak, Christine Gould, Carolyn Lowry, Alexandra C. Newton, Yuxin Mao, Robert Q. Miao, William C. Sessa, Jun Qin, Pumin Zhang, Su B,and Estela Jacinto.,The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.,EMBO J,2008,27(14):1932-43.[Link]

18.Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B.,SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.,Cell,2006,127(1):125-37.[Link]

19.Qiaojia Hunag, Jianhua Yang, Jinke Cheng, CM Walker, Z.G. Liu, and Su B.,Differential regulation of interleukin-1 receptor and toll like receptor (TLR) signaling by MEKK3,Nature Immunology,2004,5(1):98-103.[Link]

20.Yang J, Boerm M, McCarty M, Bucana C, Fidler J, Zhuang Y, and Su B.,Essential role of MEKK3 in TNF-induced NF-kB activation.,Nature Immunology,2001,2(7):620-4.[Link]

21.Su B., Jacinto, E., Hibi, M., Kallunki, T., Karin, M., and Ben-Neriah, Y..,JNK mediates signal integration during costimulation of T lymphocytes.,Cell,1994,77:727-736.[Link]