Team
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Xiaochun Xie#, Guanqin Ma#, Xiaohong Li#, Jie-Bin Zhao, Zhen Zhao*, Jianxiong Zeng*. Activation of innate immune cGAS-STING pathway contributes to Alzheimer’s pathogenesis in 5´FAD mice. Nature Aging 3, 202-212 (2023)
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Meng Zhao#, Guanqin Ma#, Xiaoxu Yan#, Xiaohong Li#, Erlin Wang, Xiang-Xiong Xu, Jie-Bin Zhao, Xueling Ma*, Jianxiong Zeng*. Microbial infection promotes amyloid pathology in a mouse model of Alzheimer’s disease via modulating γ-secretase. Molecular Psychiatry (accepted)
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Guanqin Ma#, Deng-Feng Zhang#, Qing-Cui Zou#, Xiaochun Xie#, Ling Xu, Xiao-Li Feng, Xiaohong Li, Jian-Bao Han, Dandan Yu, Zhong-Hua Deng, Wang Qu, Junyi Long, Ming-Hua Li*, Yong-Gang Yao*, Jianxiong Zeng*. SARS-CoV-2 Spike protein S2 subunit modulates γ-secretase and enhances amyloid-β production in COVID-19 neuropathy. Cell Discovery 8, 99 (2022)
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Jianxiong Zeng#, Shupeng Dong#, Zhifei Luo#, Xiaochun Xie#, Bishi Fu#, Ping Li#, Chengrong Liu#, Xing Yang, Yujie Chen, Xin Wang, Zhenshan Liu, Jing Wu, Jian-Fu Chen, Jian Zhang, Gang Long, Steven A. Goldman, Shitao Li*, Zhen Zhao*, Qiming Liang*. The zika virus capsid disrupts corticogenesis by suppressing dicer activity and miRNA biogenesis. Cell Stem Cell 27, 1-15 (2020)