Xiaoxia Wang, Associate Professor

E-mail: xiaoxiawang@shsmu.edu.cn

Research Direction：Cell Death, Inflammation and Neurodegenerative Disease

Education

2023.07-Current, Associate Professor, Songjiang Research Institute, Songjiang

District Central Hospital, Shanghai Jiao Tong University School of Medicine

2018.01-2023.06 Assistant Professor, Immunology, Shanghai Institute of

Immunology, School of Medicine, Shanghai Jiao Tong University

2017.09-2023.06 Postdoc., Immunology, Shanghai Institute of Immunology,

Shanghai, School of Medicine, Shanghai Jiao Tong University Supervisor: Bin Li

2012.09-2017.07 Ph.D., Biochemistry and Molecular Biology, Institute for

Nutritional Sciences, Chinese Academy of Sciences, Supervisor: Yong Liu

2008.09-2012.06 B.S., Biotechnology, Shandong Normal University, China

Supervisor: Jinduo Yuan

Grants

1.National Science Foundation for Young Scientists of China (2018)

2.General Financial Grant from the China Postdoctoral Science Foundation (2018)

3.Initiative Postdocs Supporting Program of School of medicine, Shanghai Jiao Tong

University

Publications

1. Shan B*, Wang X*, Wu Y*, Xu C, Xia Z, Dai J, Shao M, Zhao F, He S, Yang L, Zhang

M, Nan F, Li J, Liu J, Liu J, Jia W, Qiu Y, Song B, Han JJ, Rui L, Duan SZ, Liu Y. The

metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and

impairs energy expenditure in obesity. Nat Immunol. 2017 May;18(5):519-529.

2. Chen Y*, Wu Z*, Huang S, Wang X, He S, Liu L, Hu Y, Chen L, Chen P, Liu S, He S,

Shan B, Zheng L, Duan SZ, Song Z, Jiang L, Wang QA, Gan Z, Song BL, Liu J, Rui L,

Shao M, Liu Y. Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive

thermogenesis. Nat Metab. 2022 Sep;4(9):1166-1184.

3. Cheng H, Wang L, Yang B, Li D, Wang X, Liu X, Tian N, Huang Q, Feng R, Wang Z,

Liang R, Dai SM, Lv L, Wu J, Zang YS, Li B. Cutting Edge: Inhibition of Glycogen Synthase

Kinase 3 Activity Induces the Generation and Enhanced Suppressive Function of Human

IL-10+FOXP3+-Induced Regulatory T Cells. J Immunol. 2020 Sep 15;205(6):1497-1502.

4. Xu T, Yang L, Yan C, Wang X, Huang P, Zhao F, Zhao L, Zhang M, Jia W, Wang X, Liu

Y. The IRE1α-XBP1 pathway regulates metabolic stress-induced compensatory

proliferation of pancreatic β-cells. Cell Res. 2014 Sep;24(9):1137-40.

Awards

1.Scholarship of University of the Chinese Academy of Sciences (2012-2013)

2.Merit Student of University of the Chinese Academy of Sciences (2016-2017)

3.Poster Prize of the Cold Spring Harbor Asia Conference (2016-2017)