Location:
Yong Han Young Investigator
Email: hanyong@shsmu.edu.cn
Research area：Neurometabolic Mechanism of Obesity
Education experience
2009-2015 Zhejiang University, PhD
2004-2009 Taishan Medical college, BS
Work experience
2023.07- Now Songjiang Research Institute, Shanghai Jiao Tong University School of Medicine, Young Investigator
2023.01-2023.06 Baylor College of Medicine, Instructor
2015.09-2022.12 Baylor College of Medicine, Postdoc
Yong Han, an independent PI. He graduated in 2009 with a Bachelor of Medicine degree from Taishan Medical College. In 2015, he obtained his Ph.D. in Neuroscience from Institute of Neuroscience, Zhejiang University. In the same year, he joined Baylor College of Medicine in the United States for postdoctoral training and was appointed as an Instructor in the early 2023. In July 2023, he began his position at the Songjiang Research Institute, Shanghai Jiao Tong University School of Medicine.
Yong Han
Dr. Han's research focuses on neural circuits regulating energy metabolism, feeding behavior, and sleep-wake cycles and other innate behaviors. His research findings, as the first author, have been published in journals such as Nature Communications, Science Advances, Molecular Psychiatry, Current Biology, eLife, and he has also contributed to the writing of the neurobiology book 'Neural Regulation of Metabolism.' He has received several awards, including Outstanding Ph.D. Thesis at Zhejiang University, Hsiang-tung chang Excellent Graduate Student Paper Award, Award of Honor for Graduate, Zhejiang University, Talent Award of Beijing Institutes of Life Science, Award of the National Scholarship for Graduate Students, and CSRS-Philips Respironics Outstanding Young Investigators Award.
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Meng Wang
Email:wm19921276529@163.com
Research Direction:1. Central regulatory mechanisms of anorexia nervosa; 2. Molecular mechanisms of central inflammation and metabolic disorders induced by the obesity gene MC4R
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Xuan Zhao
Email:13231532798@163.com
Research Direction:Molecular biochemical experiments
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Han, Y., He, Y., Harris, L., Xu, Y., Wu, Q. (2023) Reversal of obesogenic feeding and hypometabolism by a bifurcating GABAergic neural circuit. eLife.
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Han, Y., Xia, G., He, Y., Farias, M., Xu, Y., Wu, Q.(2021) A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation. Sci. Adv. 7(22):eabf8719.
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Han, Y#. , Xia, G#., Srisai, D#., Meng, F., He, Y., Ran, Y., Farias, M., Hoang, G., Toth, I., Dietrich, M., Chen, MH.,Xu, Y., Wu, Q. (2021) Deciphering a novel neural circuit in distinct control of energy metabolism from feeding. Nat Commun. 12(1):3525. (#co-first author)
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Xia, G#., Han, Y#.,Meng, F., He, Y., Srisai, D., Farias, M., Dang, M., Xu, Y., Palmiter, RD., Wu, Q. (2021) Reciprocal control of obesity and anxiety–depressive disorder via a novel GABAAR and 5-HT3R pathways. Mol. Psychiatry. doi: 10.1038/s41380-021-01053-w. (#co-first author)
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Han, Y., Xia, G. &Wu, Q. (2018) Functional interrogation of the AgRP neural circuits in control of appetite, body weight, and behaviors. Adv. Exp. Med. Biol. 1090:1-16.
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Han, Y., Huang, M., Sun, M., Duan, S.& Yu, Y. (2015) Long-term synaptic plasticity in rat barrel cortex. Cereb. Cortex. 25(9):2741-51.
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Han, Y., Shi, Y., Xi, W., Zhou, R., Tan, Z., Wang, H., Li, X., Chen, Z., Feng, G., Luo, M., Huang, Z., Duan, S. & Yu, Y. (2014) Selective activation of cholinergic basal forebrain neurons induces immediate sleep-wake transitions. Curr. Biol. 24: 693-698.
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Han, Y., Yu, H., Sun, M., Wang, Y., Xi, W., Yu, Y.(2014) Astrocyte-restricted disruption of connexin-43 impairs neuronal plasticity in mouse barrel cortex. Eur. J. Neurosci. 39: 35-45.
